The Philadelphia Phillies remain in Chicago to face the Cubs at 7:00 PM ET. It’s Sunday Night Baseball on ESPN and the final game of a three-game set. Can the Cubs win the game outright as money-line home underdogs? Keep reading for our Phillies vs. Cubs betting prediction.
Projected starting pitchers: Aaron Nola (PHI) vs. Jameson Taillon (CHC)
The Philadelphia Phillies are 14-13 straight up this year. They are 4-6 straight up in their last 10 games. The Phillies are 14-13 ATS this season.
The Chicago Cubs are 17-11 straight up this year. They are 6-4 straight up in their last 10 games. The Cubs are 15-13 ATS this season.
Phillies vs. Cubs Game Matchup and Betting Odds
961 Philadelphia Phillies (-115) at 962 Chicago Cubs (-105); o/u 7.5
7:00 PM ET, Sunday, April 27, 2025
Wrigley Field, Chicago, IL
TV: ESPN
Phillies vs. Cubs Public Betting Information
Our MLB Public Betting Information page indicates that 54% of public bettors are currently backing the Phillies money line. Please note that these numbers are subject to change all the way up to game time, so be sure to check the link to ensure that you’re receiving the most up-to-date public betting data.
Philadelphia Phillies DFS Spin
Phillies left fielder Max Kepler led the team in hits in their 10-4 win over the Cubs on Saturday. In that game, the left-handed hitter from Berlin, Germany, went 3 for 5 with a homer, 2 RBIs, and 2 runs scored. For the season, Kepler is batting .267 with 2 home runs, 6 RBIs, and an OPS of .764. Max Kepler is hitting .385 in his last 7 games, making him an intriguing DFS option on Sunday.
Chicago Cubs DFS Spin
Cubs designated hitter Seiya Suzuki drove in most of his team’s runs in their 10-4 loss to the Phillies on Saturday. Hitting out of the #2 spot in the lineup, the 30-year-old from Tokyo, Japan, went 2 for 4 with 2 singles and 3 RBIs. Suzuki is batting .292 with 6 homers, 23 RBIs, 1 stolen base, and an OPS of .913 this year. The right-handed hitter is batting .292 in night games this season. That fact makes Seiya Suzuki worth a look in most DFS formats on Sunday night.
Phillies vs. Cubs MLB Betting Trends
Philadelphia is 1-5 straight up in their last 6 games overall.
Philadelphia is 5-9 straight up as the road team this season.
Chicago is 5-2 straight up in their last 7 games overall.
Chicago is 8-2 straight up after a loss this season.
Phillies vs. Cubs Betting Prediction
I like the Cubs in this matchup. A few relevant numbers will underscore why. Chicago is 9-4 straight up as the home team and 17-11 straight up in non-division games this season. What’s more, the Cubs are 12-9 straight up when playing on no rest and 15-11 straight up when playing an opponent on equal rest this season. And finally, Chicago is 12-10 straight up in National League games and 2-1 straight up as a home underdog this season. For all of those reasons, I think the Cubs will triumph over the Phillies on Sunday Night Baseball. The pick is Chicago -105 over Philadelphia at Bovada.lv.