49ers vs Rams Odds & Prediction
NFC West rivals clash in L.A. on Sunday afternoon when the Rams the 49ers at 4:25 p.m. ET.
After the Niners took the first meeting between these two teams in Santa Clara, will the Rams cash as a small home dog in the rematch?
Game Matchup & Betting Odds
273 San Francisco 49ers (-1) at 274 Los Angeles Rams (+1); o/u 41.5
4:25 p.m. ET, Sunday, October 30, 2022
SoFi Stadium, Los Angeles, CA
49ers vs. Rams Public Betting Information
Our NFL Public Betting Information page indicates that 71% of public bettors are currently backing the 49ers when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
San Francisco 49ers DFS Spin
Deebo Samuel (hamstring) will not play in Week 8 against the Rams. “Day-to-day” with the hamstring injury at the start of the week, Deebo didn’t practice all week. The 49ers will go on bye for Week 9 so he’ll get an extra week of rest. Christian McCaffrey should draw more targets in his second week with the 49ers, and Brandon Aiyuk and George Kittle could also see more offensive participation with Deebo out.
Los Angeles Rams DFS Spin
Rams activated WR Van Jefferson from injured reserve. Jefferson will officially be active in Week 8 for the first time this season. Considering the relative struggles of Allen Robinson and poor schematic fit for Ben Skowronek on the perimeter, there is opportunity for Jefferson to immediately step back into the WR2 role for the Rams. Consider Jefferson an upside WR3 piece in his downfield role against the 49ers.
49ers vs. Rams Betting Trends
Under is 5-1 in the last 6 meetings
Underdog is 7-1 ATS in their last 8 meetings
49ers are 4-0 ATS in their last 4 meetings in Los Angeles
49ers are 6-0 ATS in their last 6 meetings
49ers vs. Rams Prediction:
The Niners are 5-11 against the spread in their last 16 games after allowing more than 250 yards passing in their previous game, while the Rams are 11-4-1 against the number in their last 16 games coming off a bye. The Rams have also covered in four straight games after allowing less than 250 total yards in their previous game and are 4-0 at the betting window in their last four games after allowing less than 150 yards passing in their previous contest.
NFL WEEK 8 PREDICTION: LOS ANGELES RAMS +1