The Sunday Night Football matchup sets up to be fantastic, as the 49ers will host the Cowboys at 8:20 p.m. ET. With San Francisco listed as 3.5-point home favorites and the total sitting at 45, what’s the best bet for this Cowboys vs. 49ers matchup?
Game Matchup & Betting Odds
473 Dallas Cowboys (+3.5) at 474 San Francisco 49ers (-3.5); o/u 45
8:20 p.m. ET, Sunday, October 8, 2023
Levi’s Stadium, Santa Clara, CA
TV: NBC
Cowboys vs. 49ers Public Betting Information
Our NFL Public Betting Information page indicates that 67% of public bettors are currently backing the Chiefs when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
Dallas Cowboys DFS Spin
Cowboys removed Tyron Smith (knee) from the Week 5 injury report against the 49ers. The Cowboys will have their starting offensive line completely intact for the first time all season. In addition to Smith being removed from the injury report, left guard Zack Martin (thigh) was also removed from the injury report after logging two full practices to close out the week. It’s a timely return for both players, who will have their hands full protecting Dak Prescott from Nick Bosa and the 49ers’ pass rush.
San Francisco 49ers DFS Spin
Deebo Samuel (knee/ribs) was removed from the Week 5 injury report and will play against the Cowboys. Samuel played through a questionable tag last week and wasn’t even given a designation this time around. Things appear to be progressing in the right direction for the versatile receiver, though he may still be playing slightly banged up on Sunday. Samuel will rank as a WR2 for his date with Dallas. Jauan Jennings was also removed from the Week 5 injury report.
Cowboys vs. 49ers Betting Trends
The total has gone UNDER in 5 of Dallas’s last 6 games on the road
Dallas is 4-1 SU in its last 5 games when playing on the road against San Francisco
San Francisco is 5-0 ATS in its last 5 games at home
The 49ers are 5-0 SU in their last 5 games at home
Cowboys vs. 49ers Prediction:
Give me San Francisco. This is when the injury to defensive back Trevon Diggs will come into play for Dallas. The Niners have a multitude of ways to beat opponents, from lining up Christian McCaffrey and Samuel all over their formations, to winning on the outside of Brandon Aiyuk. Brock Purdy is an excellent point guard in this offense and Kyle Shanahan knowns Dan Quinn well from their time in Atlanta.
Despite their 3-1 start, the Cowboys have also struggled in the red zone this season. Dak Prescott cost them dearly in their loss to the Cardinals in Week 3 and this is the first time Dallas is facing a good team this season. There’s no doubt Dallas is a playoff team. That said, San Francisco is a legit Super Bowl contender.
Cowboys vs. 49ers NFL Prediction: SAN FRANCISCO 49ERS -3.5