The Buffalo Bills head to London to take on the Jaguars on Sunday morning when Week 5’s slate begins at 9:30 AM ET on NFL Network. Can the Jaguars cover the 5.5-point spread as neutral-site underdogs? Check out our Jaguars vs. Bills betting prediction to see who prevails in London.
The Jacksonville Jaguars are 2-2 straight up and 2-2 against the spread this year. Their best win came against the Falcons, and their worst loss came against the Texans.
The Buffalo Bills are 3-1 straight up on the year and 3-1 against the spread. Their best win came against the Dolphins, and their lone loss came against the Jets.
Game Matchup & Betting Odds
451 Jacksonville Jaguars (+5.5) vs. 452 Buffalo Bills (-5.5); O/U 48.5
9:30 AM ET, Sunday, October 8, 2023
Tottenham Hotspur Stadium, London, England
Jaguars vs. Bills Public Betting Information
Our NFL Public Betting Information page indicates that the public favors the Bills in this game. According to our numbers, 77% of public bets are on Buffalo -5.5. Please note that this information is subject to change all the way up to kickoff, so be sure to check the link before you pick so you’re receiving the most accurate and up-to-date public betting data.
Jacksonville Jaguars DFS Spin
Starting Jacksonville wide receiver Zay Jones has missed the team’s last two games with a knee injury, and he’s officially listed as questionable for Sunday’s game in London. Jones had 5 catches for 55 yards and a touchdown in the Jaguars’ Week 1 win over the Colts but went without a reception in his team’s Week 2 game against the Chiefs.
Jaguars starting inside linebacker Devin Lloyd missed the team’s last game with a hand injury, and he’ll miss Sunday’s game as well. Lloyd is fifth on the team with 19 total tackles and is tied for second on the club with 3 passes defended on the year.
Buffalo Bills DFS Spin
Buffalo starting defensive end Greg Rousseau won’t suit up on Sunday as he’s dealing with a foot injury. Rousseau is tied for second on the team with 3 sacks this season.
Bills starting cornerback Tre’Davious White suffered a torn Achilles tendon in his team’s win over Miami last Sunday. That injury will keep him out for the rest of the year. White had 2 passes defended and an interception in 4 games for Buffalo this season.
Buffalo’s other starting cornerback, Christian Benford is questionable for this weekend’s game with a shoulder injury. If Benford can’t go, Buffalo will likely insert second-year first-round pick Kaiir Elam in his place.
Jaguars vs. Bills Betting Trends
Jaguars quarterback Trevor Lawrence is 17-23 ATS in his career.
Trevor Lawrence is 24-16 to the under in his career.
Bills quarterback Josh Allen is 31-16-3 ATS on normal (6 days) rest.
Josh Allen is 24-16-3 ATS away from home.
Jaguars vs. Bills Prediction:
Bills QB Josh Allen is still one of the best in the league this season. He and the Bills have appeared to right the ship after their odd loss to the Zach Wilson-led Jets in Week 1. Since that game, the Bills are 3-0 straight up with an average victory margin of 30 points per game. There’s also the fact that of Josh Allen’s 59 career wins as a starting QB, 45 of those have come by 7 points or more. Favorites have fared well outside the United States. The favorites are 26-14 ATS in international games since the NFL began playing games outside the USA. For all of those reasons, I’m laying the points with the Bills in London on Sunday morning.