Jaguars vs. Colts Prediction & Odds
The Jacksonville Jaguars travel to Indianapolis to play the Colts on Sunday afternoon when Week 6’s NFL Sunday early slate begins at 1:00 PM ET.
Can Jacksonville pull off the minor upset and triumph as 2-point road underdogs?
The Jacksonville Jaguars are 2-3 through their first 5 games of 2022. They beat the Colts and Chargers but lost to the Commanders, Eagles, and Texans. The Jaguars are 2-3 ATS this year.
The Indianapolis Colts are 2-2-1 so far this season. They beat the Chiefs and Broncos but dropped games to the Jaguars and Titans. They tied the Texans in Week 1. The Colts are 2-3 ATS on the year.
Game Matchup & Betting Odds
255 Jacksonville Jaguars +2 at 256 Indianapolis Colts -2; o/u 42
1:00 p.m. ET, Sunday, October 16, 2022
Lucas Oil Stadium, Indianapolis, IN
Jaguars vs. Colts Public Betting Information
Our NFL Public Betting Information page indicates that the public is slightly favoring the Jaguars in this game. According to our numbers, 58% of public bets are on the Jaguars +2. Please note that this information is subject to change all the way up to kickoff, so make sure to check the link before you pick so you’re receiving the most accurate and up-to-date public betting data.
Jacksonville Jaguars DFS Spin
Jaguars wide receiver Zay Jones is questionable with an ankle injury and was limited at practice on Thursday. That should provide more opportunities for wide receivers Christian Kirk and Marvin Jones Jr. Kirk had 6 catches for 78 yards and 2 touchdowns in the Jags’ Week 2 win over the Colts a month ago. For another pass-catching option, I’d consider tight end Evan Engram. The 2017 first-round pick out of Ole Miss had one of his best games of the season against Indy in Week 2, posting 7 catches for 46 yards. I’d think twice about using Jacksonville running backs James Robinson and Travis Etienne Jr. because Indianapolis is only allowing 3.4 yards per rushing attempt, which is the second-best mark in the league. I’d take a look at the Jags’ defense as a sleeper pick, as they’re averaging 1.8 takeaways per game, tied for fifth-best in the NFL.
Indianapolis Colts DFS Spin
For the Colts, their top two running backs, Jonathan Taylor and Nyheim Hines are listed as questionable for Sunday’s contest. They were both limited in practice on Thursday, with Taylor nursing an ankle injury and Hines recovering from a concussion. If neither Taylor nor Hines can play, the beneficiaries will be running backs Deon Jackson and Philip Lindsay, who combined to rush for 102 yards against Denver last week. Jackson will be the better option of the two as he averaged 4.8 yards per carry on 13 rushing attempts against the Broncos.
The Colts’ number two wide receiver Ashton Dulin has been placed on injured reserve with a foot ailment. This has paved the way for rookie wide receiver Alec Pierce. The second-round pick out of Cincinnati has been coming on of late, recording at least 80 receiving yards in each of the Colts’ past two games. He could see a good share of targets on Sunday, especially if the Colts are trailing and need to get back in the game.
Jaguars vs. Colts Betting Trends
The underdog is 6-0 ATS in the last 6 meetings between Jacksonville and Indianapolis.
Jacksonville is 13-2-1 ATS in their last 16 games against Indianapolis.
Jacksonville is 5-1-1 ATS in their last 7 games at Indianapolis.
Indianapolis is 0-4 ATS in their last 4 games against the AFC South.
Jaguars vs. Colts Prediction:
The statistic that really tells the story of this matchup is points per game. The Indianapolis Colts are only averaging 13.8 points per game, the worst mark in the league. They may be missing multiple skill players for this game. The Jacksonville Jaguars are only allowing 16 points per game, which is tied for the fourth-best mark in the league. I don’t think Matt Ryan and the Colts can score enough points to win and cover the game. The Jacksonville money line at +110 is an attractive bet, but I’ll take the Jaguars and the points.
NFL WEEK 6 PREDICTION: JACKSONVILLE JAGUARS +2
