Saints vs. 49ers Prediction & Odds
The over has been profitable in previous meetings between the Saints and 49ers, who will square off in Santa Clara on Sunday at 4:25 p.m. ET. With the number sitting at 43 points, is the over the best play on the board today?
Game Matchup & Betting Odds
271 New Orleans Saints (+8.5) at 272 San Francisco 49ers (-8.5); o/u 43
4:25 p.m. ET, Sunday, November 27, 2022
Levi’s Stadium, Santa Clara, CA
Saints vs. 49ers Public Betting Information
Our NFL Public Betting Information page indicates that 56% of public bettors are currently backing the 49ers when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.
New Orleans Saints DFS Spin
Alvin Kamara had 12 rushes for 42 yards in New Orleans’ Week 11 win over Los Angeles, adding four receptions for 47 yards on five targets. Outrushed by Taysom Hill, Kamara saw just two red zone touches and zero targets, none of which happened on goal-to-go. The opportunity was there for more, but the Saints got sacked out of a few red zone looks and the ball did not go Kamara’s way. He’ll be a borderline RB1 in a tough matchup against the 49ers, particularly if the Saints can’t get any of their better offensive linemen back.
San Francisco 49ers DFS Spin
Deebo Samuel (hamstring) is questionable for San Francisco’s Week 12 game against the Saints. Samuel practiced thrice this week — mostly limited — and some 49ers beats believed he’d be taken off the report entirely today. Samuel has dealt with hamstring issues most of this season and has generally played through it when he’s practiced. We’d tentatively believe he’s on the optimistic side of questionable before hearing Kyle Shanahan speak on it.
Saints vs. 49ers Betting Trends
Saints are 2-6 ATS in their last 8 meetings
Road team is 5-1 ATS in their last 6 meetings
Saints are 38-18 ATS in their last 56 road games
49ers are 15-7 ATS in their last 22 games overall
Saints vs. 49ers Prediction:
The over is 6-0 in the last six meetings between these two teams when the game is in San Francisco and is 7-2-1 in the last 10 meetings overall. The over is also 4-0 in the Saints’ last four conference games, is 4-1 in their last five games coming off an ATS win and has cashed in 19 of their last 28 games after accumulating less than 90 yards rushing in their previous contest.
NFL WEEK 12 PREDICTION: SAINTS/49ERS OVER 43
