Titans vs. Colts Prediction: Can Mason Rudolph spark Titans?

Titans vs. Colts Titans vs. Colts

The Tennessee Titans head to Indianapolis to face the Colts on Sunday when Week 16’s early slate begins at 1:00 PM ET on CBS. Can the Colts cover the 3.5-point spread as home favorites? Keep reading for our Titans vs. Colts betting prediction.

The Tennessee Titans are 3-11 straight up and 2-12 against the spread this year. Their best win came against Houston, and their worst loss came against Jacksonville.

The Indianapolis Colts are 6-8 straight up and 8-6 against the spread this season. Their best win came against Pittsburgh, and their worst loss came against Jacksonville.

Titans vs. Colts Matchup & Betting Odds

117 Tennessee Titans (+3.5) at 118 Indianapolis Colts (-3.5); o/u 42.5

1:00 p.m. ET, Sunday, December 22, 2024

Lucas Oil Stadium, Indianapolis, IN

TV: CBS

Titans vs. Colts Public Betting Information

Our NFL Public Betting Information page indicates that 61% of public bettors are currently backing the Colts when it comes to the spread. This information is subject to change throughout the day, however, so be sure to check the link so you’re receiving the most up-to-date public betting data.

Tennessee Titans Daily Fantasy Spin

Titans cornerback L’Jarius Sneed (quadriceps), wide receiver Colton Dowell (knee), and linebacker Luke Gifford (concussion) will all sit out Sunday’s road date with the Colts. Gifford has 33 total tackles, an interception, and a pass defended in 14 games this season.

Tennessee running back Tony Pollard (ankle), quarterback Will Levis (shoulder), linebacker Kenneth Murray Jr. (hamstring), place kicker Nick Folk (abdomen), and linebacker Otis Reese IV (ankle) are all officially listed as questionable to play this weekend. 

Titans head coach Brian Callahan said that Murray and Folk would be game-time decisions. Mason Rudolph will start at quarterback on Sunday, so Will Levis will likely serve as the backup if he’s healthy enough to suit up this weekend.

Indianapolis Colts Daily Fantasy Spin

Colts cornerback JuJu Brents (knee), wide receiver Alec Pierce (concussion), linebacker E.J. Speed (knee), and offensive tackle Braden Smith (personal) will all miss Sunday’s game against the Titans. 

Indianapolis wide receiver Ashton Dulin (ankle), tight end Mo Alie-Cox (hip), and place kicker Matt Gay (neck) are all listed as questionable to play this weekend. Colts rookie wideout Adonai Mitchell should see an increase in playing time with Alec Pierce out of the lineup and Ashton Dulin’s questionable injury status ahead of Sunday’s contest.

Tennessee is 26-25 ATS in division games since the start of the 2016 season.

Tennessee is 6-4 ATS in their last 10 games against Indianapolis.

Indianapolis is 12-16 ATS in division games since the start of the 2020 season.

Indianapolis is 12-13 ATS after a loss since the beginning of the 2022 season.

Titans vs. Colts Betting Prediction:

Tennessee quarterback Mason Rudolph has started 3 games this season. The Oklahoma State product is 1-2 straight up and 0-3 ATS in those starts. Rudolph’s two outright losses came against teams with elite offenses (Detroit and Buffalo). The Colts do not have a great offense. Indianapolis is 23rd in the NFL in points per game and 21st in the league in points per play this season.

This is largely due to the ineptitude of Colts quarterback Anthony Richardson. Richardson has a touchdown-pass-to-interception ratio of 7-11, a completion percentage of 47.0%, and a QBR of 45.7 this season. He’s 1-3 against the spread as the starter in his last 4 outings. I can’t back him when the Colts are giving more than a field goal against a divisional opponent. I’m taking the Titans and the points on the road in Indy on Sunday afternoon.

NFL Week 16 Titans vs. Colts Betting Prediction: TENNESSEE TITANS +3.5

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